Minocycline reveals neuroprotection in an accelerated rhesus macaque model of neuroAIDS by 1H MR Spectroscopy
نویسندگان
چکیده
E-M. Ratai, C-G. Joo, J. Bombardier, J. He, L. Annamalai, T. H. Burdo, J. H. Campbell, C. Soulas, P. Autissier, S. V. Westmoreland, K. Williams, and R. G. Gonzalez Radiology, Massachusetts General Hospital A.A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, New England Regional Primate Research Center, Southborough, MA, United States, Biology Department, Boston College, Boston, MA, United States
منابع مشابه
Proton Magnetic Resonance Spectroscopy Reveals Neuroprotection by Oral Minocycline in a Nonhuman Primate Model of Accelerated NeuroAIDS
BACKGROUND Despite the advent of highly active anti-retroviral therapy (HAART), HIV-associated neurocognitive disorders continue to be a significant problem. In efforts to understand and alleviate neurocognitive deficits associated with HIV, we used an accelerated simian immunodeficiency virus (SIV) macaque model of NeuroAIDS to test whether minocycline is neuroprotective against lentiviral-ind...
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E-M. Ratai, S. Pilkenton, J. Bombardier, C-G. Joo, K. W. Turk, M. R. Lentz, J. He, L. Annamalai, S. O' Neil, S. V. Westmoreland, T. H. Burdo, J. H. Campbell, C. Soulas, P. Autissier, W-K. Kim, K. Williams, and R. G. Gonzalez Radiology, Massachusetts General Hospital A.A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, Harvard Medical School, Boston, MA, United States, Ne...
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